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KMID : 1037820130020010012
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Journal of Pain and Autonomic Disorders
2013 Volume.2 No. 1 p.12 ~ p.19
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Overview of Raynaud’s Phenomenon
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Ahn Joong-Kyong
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Abstract
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Raynaud’s phenomenon (RP) is a frequent and reversible vasospastic disorder of peripheral arterioles. It was characterized by episodic attacks of well demarcated color changes with numbness and pain of the digits in
response to cold temperature or emotional stress. Raynaud’s phenomenon should be distinguished from secondary RP to an underlying disease, mainly systemic sclerosis. Although the pathogenesis of RP is incompletely understood, imbalance between vasoconstricting and vasodilating factors, (in favor of vasoconstriction) via different mechanisms is thought to contribute the pathogenesis of RP. Diagnosis of RP is based on the history of triphasic color changes in the digits (pallor, cyanosis and hyperemia). Understanding the pathogenesis and epidemiology is essential to the appropriate categorization of patients and judicious use of treatment options. The goal in the treatment of RP is to improve the quality of life and prevent the critical ischemia. This review discusses the pathophysiology, diagnosis, differential diagnosis and medical treatment of Raynaud’s phenomenon.
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KEYWORD
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Raynaud’s phenomenon, Diagnosis, Treatment
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